We know our biological limitations because we have come up with some devises which have the grater capabilities than our senses. This is still not true with math and physics. These two are just developed based on human brain's ability to interpret the natural phenomena. Till date we do not have any machine which can over perform the human brain in math and physics(someday artificial intelligence might do that), so there is really no way to judge whether the math or physics we do is correct or not. Our math and physics are based on certain unproved assumptions which are based on the way human brain interprets these phenomena, so we cannot be 100% sure that the math and physics we do is correct or not